1.C. Huang#, C. Yang#, W. Zhang, L. Zhang, B. C. De, Y. Zhu, X. Jiang, C. Fang, Q. Zhang, C. Yuan, H. Liu*, and C. Zhang*. Molecular basis of dimer formation during the biosynthesis of benzofluorene-containing atypical angucyclines. Nature Communications, 2018, 9(1): 2088.
2.B. Enghiad#, C. Huang#, F. Guo, G. Jiang, B. Wang, S. Tabatabaei, T. Martin, and H. Zhao*. Cas12a assisted precise targeted cloning using in vivo Cre-lox recombination. Nature Communications, 2021, 12(1): 1171.
3.C. Huang, H. Cui, H. Ren, and H. Zhao*. Investigation of the biosynthetic mechanism of bipentaromycin featuring an unprecedented cyclic head-to-tail dimeric scaffold. JACS Au, 2023, 3(1), 195−203.
4.C. Huang, C. Yang*, W. Zhang, L. Zhang, Y. Zhu, and C. Zhang*. Discovery of an unexpected 1,4-oxazepine-linked seco-fluostatin heterodimer by inactivation of the oxidoreductase-encoding gene flsP. Journal of Natural Products, 2021, 84(8): 2336–2344.
5.C. Yang#, C. Huang#, C. Fang, L. Zhang, S. Chen, Q. Zhang, C. Zhang*, and W. Zhang*. Inactivation of flavoenzyme-encoding gene flsO1 in fluostatin biosynthesis leads to diversified angucyclinone derivatives. The Journal of Organic Chemistry, 2021, 86(16): 11019–11028.
6.C. Huang, C. Yang, Y. Zhu*, W. Zhang, C. Yuan, and C. Zhang*. Marine bacterial aromatic polyketides from host-dependent heterologous expression and fungal mode of cyclization. Frontiers in Chemistry, 2018, 6(10): 528.
7.C. Huang, C. Yang, Z. Fang, L. Zhang, W. Zhang, Y. Zhu, and C. Zhang*. Discovery of stealthin derivatives and Implication of the amidotransferase FlsN3 in the biosynthesis of nitrogen-containing fluostatins. Marine Drugs, 2019, 17(3): 150.
8.C. Huang, C. Yang, W. Zhang, Y. Zhu, L. Ma, Z. Fang, and C. Zhang*. Albumycin, a new isoindolequinone from Streptomyces albus J1074 harboring the fluostatin biosynthetic gene cluster. Journal of Antibiotics, 2019, 72(5): 311−315.
9.C. Huang, S. Luo, Y. Li, C. Li, J. Hua, Y. Liu, S. Jing, Y. Wang, M. Yang, and S. Li*. Antifeedant and antiviral diterpenoids from the fresh roots of Euphorbia jolkinii. Natural Products and Bioprospecting, 2014, 4(2): 91−100.
10.G. Jiang, C. Huang, W. Harrison, H. Li, M. Zhou, and H. Zhao*. Ene reductase enabled intramolecular β‐C−H functionalization of substituted cyclohexanones for efficient synthesis of bridged bicyclic nitrogen scaffolds. Angewandte Chemie International Edition, 2023. doi.org/10.1002/anie.202302125.
11.H. Ren, S. Dommaraju, C. Huang, H. Cui, Y. Pan, M. Nesic, L. Zhu, D. Sarlah, D. Mitchell*, and H. Zhao*. Genome mining unveils a class of ribosomal peptides with two amino termini. Nature Communications, 2023, 14(1): 1624.
12.B. Wang, F. Guo, C. Huang, and H. Zhao*. Unraveling the iterative type I polyketide synthases hidden in Streptomyces. Proceedings of National Academy of Sciences of the United States of America, 2020, 117(15): 8449−8454.
13.C. Yang#, L. Zhang#, W. Zhang, C. Huang, Y. Zhu, X. Jiang, W. Liu, M. Zhao, B. C. De, and C. Zhang*. Biochemical and structural insights of multifunctional flavin-dependent monooxygenase FlsO1-catalyzed unexpected xanthone formation. Nature Communications, 2022, 13(1): 5386.
14.B. C. De#, W. Zhang#, C. Yang, A. Mándi, C. Huang, L. Zhang, W. Liu, M. W. Ruszczycky, Y. Zhu, M. Ma, G. Bashiri, T. Kurtán, H. Liu*, and C. Zhang*. Flavin-enabled reductive and oxidative epoxide ring opening reactions. Nature Communications, 2022, 13(1): 4896.
15.C. Yang, C. Huang, W. Zhang*, Y. Zhu, and C. Zhang*. Heterologous expression of fluostatin gene cluster leads to a bioactive heterodimer. Organic Letters, 2015, 17 (21): 5324-5327.
16.W. Zhang#, C. Yang#, C. Huang, L. Zhang, H. Zhang, Q. Zhang, C. Yuan, Y. Zhu, and C. Zhang*. Pyrazolofluostatins A−C, pyrazole-fused benzo[a]fluorenes from South China sea-derived Micromonospora rosaria SCSIO N160. Organic Letters, 2017, 19(3): 592−595.
17.S. Luo, C. Huang, J. Hua, S. Jing, L. Teng, T. Tang, Y. Liu*, and S. Li*. Defensive specialized metabolites from the latex of Euphorbia jolkinii. Journal of Chemical Ecology, 2023, 10.1007/s10886-023-01413-6.