1.Zhicheng Xie#, Lin Li#, Yihao Guo, Mi Zhang, Taiwen Chen, Yongpeng Li, Xin Li, Xi Zhu, Yu Zhang, Liguang Lou*, Youhong Hu*, Discovery of novel heteroaryl alkynes for highly potent KITD816V cells inhibition to treat gastrointestinal stromal tumors, Acta Pharmaceutica Sinica B, 2022, 12, 4004-4007.

2.Sheng Han#, Heng Li#, Weixiong Chen, Li Yang, Xiankun Tong*, Jianping Zuo*, Youhong Hu*, Discovery of potent ebola entry inhibitors with (3S,4aS,8aS)-2-(3-amino-2-hydroxypropyl) decahydroisoquinoline-3-carboxamide scaffold, European Journal of Medicinal Chemistry, 2022, 240, 114608.

3.Jingjing Chen#, Huixin He #, Aihuan Wei, Yalei Li, Gang Cheng, Hui Qin, Hanyue Zhong, Hongchun Liu, Meiyu Geng, Aijun Shen*, Youhong Hu*, Adjusted degradation of BRD4 S and BRD4 L based on fine structural modifications of the pyrrolopyridone scaffold, European Journal of Medicinal Chemistry, 2022,236, 114259.

4.Jinxin Che, Zhilong Wang, Zheyuan Shen, Weihao Zhuang, Huazhou Ying, Yongzhou Hu, Youhong Hu*, Xin Xie*, and Xiaowu Dong*, Discovery of 1,5-Dihydro‑4H‑imidazol-4-one Derivatives as Potent, Selective Antagonists of CXC Chemokine Receptor 2, ACS Med. Chem. Lett. 2021, 12, 836−845. 

5.Zhicheng Xie#, Caigui Xiang#, Xin Li, Chen Fan, Taiwen Chen, Moting Liu, Yanjie Ma, Fang Bai, Wei Tang,* and Youhong Hu*, Discovery of Potent Antiallergic Agents Based on ano‑Aminopyridinyl Alkynyl Scaffold, J. Med. Chem, 2021, 64 (18), 13588-13603. 

6.Jingjing Chen#; Yalei Li#; Jie Zhang; Minmin Zhang ; Aihuan Wei ; Hongchun Liu ; Zhicheng Xie ; Wenming Ren ; Wenwen Duan ; Zhuo Zhang; Aijun Shen* ; Youhong Hu*; Discovery of selective HDAC/BRD4 dual inhibitors as epigenetic probes, European Journal of Medicinal Chemistry, 2021, Vol209, 112868.

7.Congcong Wang#, Yu-Fang Zhang#, Shimeng Gu#, Quan Zhao, Yanping Zeng, Zhicheng Xie, Xin Xie*, Boxun Lu*, and Youhong Hu* ,GPR52 Antagonist Reduces Huntingtin Levels and Ameliorates Huntington’s Disease-Related Phenotypes, J. Med. Chem, 2021, 64, 941-957. 

8.Wen-Di Duan, Yu-Fang Zhang, and Youhong Hu*,NaH Promoted One-Pot Tandem Reactions of 3‑(1-Alkynyl) Chromones to Form 2‑Nitrogen-Substituted Xanthones, ACS Omega, 2020, 5, 13454−13461. 

9.Wuhong Chen,# Feifei Liu,# Qiliang Zhao,# Xinna Ma, Dong Lu, Heng Li, Yanping Zeng, Xiankun Tong, Limin Zeng, Jia Liu, Li Yang,* Jianping Zuo,* and Youhong Hu*, Discovery of Phthalazinone Derivatives as Novel Hepatitis B Virus Capsid Inhibitors, J. Med. Chem., 2020, 63(15): 8134-8145. 

10.Zhicheng Xie#; Bing Wu #; Yingqiang Liu#; Wenming Ren; Linjiang Tong; Caigui Xiang; Aihuan Wei; Yuanzhuo Gao; Limin Zeng; Hua Xie*; Wei Tang*; Youhong Hu*; Novel Class of Colony-Stimulating Factor 1 Receptor Kinase Inhibitors Based on an o-Aminopyridyl Alkynyl Scaffold as Potential Treatment for Inflammatory Disorders, J. Med. Chem., 2020, 63 (3): 1397-1414. 

11.Yu Lei#,Wenming Ren#, Cheng-Kun Wang, Rong-Rong Tao, Huai-Jiang Xiang, Li-Li Feng, Yin-Ping Gao, Quan Jiang, Xin Li*, Youhong Hu*, Feng Han*, Visualizing Autophagic Flux during Endothelial Injury with a Pathway-Inspired Tandem-Reaction Based Fluorogenic Probe, Theranostics 2019, Vol. 9, Issue 19, 5672-5680. 

12.Yu-Fang Zhang, Wen-Di Duan, Jingjing Chen, and Youhong Hu*, Base-Promoted Cascade Reactions of 3‑(1-Alkynyl)chromones with Pyridinium Ylides to Chromeno[2,3-d]azepine Derivatives, J. Org. Chem., 2019, 84, 4467−4472.

13.Wenming Ren#, Jingjing Zhang#, Cheng Peng#, Huaijiang Xiang, Jingjing Chen, Chengyuan Peng, Weiliang Zhu, Ruimin Huang,* Haiyan Zhang,* and Youhong Hu*, Fluorescent Imaging of β‑Amyloid Using BODIPY Based Near-Infrared Off−On Fluorescent Probe, Bioconjugate Chem. 2018, 29, 3459−3466. 

14.Wenming Ren#, Huaijiang Xiang#, Chengyuan Peng, Zulipali Musha, Jingjing Chen, Xin Li, Ruimin Huang*, and Youhong Hu*, Direct C–H functionalization of difluoroboron dipyrromethenes (BODIPYs) at b-position by iodonium salts, RSC Advances, 2018, 8, 5542–5549. 

15.Dong Lu#, Jianan Liu#, Yunzhe Zhang#, Feifei Liu, Limin Zeng, Runze Peng, Li Yang, Huazhou Ying, Wei Tang, Wuhong Chen, Jianping Zuo, Xiankun Tong*, Tao Liu*, Youhong Hu*, Discovery and optimization of phthalazinone derivatives as a new class of potent dengue virus inhibitors, European Journal of Medicinal Chemistry, 2018, 145, 328-337. 

16.Dong Lu#, Juan Yan#, Lang Wang, Hongchun Liu, Limin Zeng, Minmin Zhang, Wenwen Duan, Yinchun Ji, Jingchen Cao, Meiyu Geng, Aijun Shen*, and Youhong Hu*, Design, Synthesis, and Biological Evaluation of the First c-Met/HDAC Inhibitors Based on Pyridazinone Derivatives, ACS Med. Chem. Lett., 2017, 8 (8), 830–834. 

17.Jianwei Yan#, Gaihong Wang#, Xiangyu Dang, Binbin Guo, Wuhong Chen, Ting Wang, Limin Zeng, Heyao Wang*, Youhong Hu*, Discovery of a low-systemic-exposure DGAT-1 inhibitor with a picolinoylpyrrolidine-2-carboxylic acid moiety, Bioorgan. Med. Chem., 2017, 25, 4701-4714.

18.Shan Li, Penghui Wan, Jing Ai, Rong Sheng*, Yongzhou Hu*, and Youhong Hu*, Palladium-Catalyzed, Silver-Assisted Direct C-5–H Arylation of 3-Substituted 1,2,4-Oxadiazoles under Microwave Irradiation, Adv. Synth. Catal., 2017, 359, 772 –778. 

19.Dong Lu#, Feifei Liu#, Weiqiang Xing, Xiankun Tong, Lang Wang, Yajuan Wang, Limin Zeng, Chunlan Feng, Li Yang*, Jianping Zuo*, and Youhong Hu*, Optimization and Synthesis of Pyridazinone Derivatives as Novel Inhibitors of Hepatitis B Virus by Inducing Genome-free Capsid Formation, ACS Infect. Dis., 2017, 3 (3), 199–205. 

20.Yang Liu#, Xia Peng#, Xiaocong Guan#, Dong Lu, Yong Xi, Shiyu Jin, Hui Chen, Limin Zeng, Jing Ai*, Meiyu Geng*, Youhong Hu*, Discovery of novel Ponatinib analogues for reducing KDR activity as potent FGFRs inhibitors, Eur. J. Med. Chem., 2017, 126, 122-132.